Every peptide, rated by the evidence behind it.

Not a peptide: a permanently charged N-methylated quinolinium cation, handled as its iodide salt, acting as a substrate-site inhibitor of nicotinamide N-methyltransferase (NNMT)

C-terminal fragment of human growth hormone (residues 176–191)

Long-acting amylin analog

GLP-1 analog fused to a modified human IgG4 Fc fragment

GLP-1 receptor agonist — synthetic exendin-4, from Gila monster venom

Endogenous 29-residue single-chain peptide hormone secreted by pancreatic alpha cells; the physiological counter-regulator to insulin

Endogenous 51-residue two-chain peptide hormone (A-chain 21 residues, B-chain 30 residues) joined by two interchain disulfide bridges; therapeutic versions are recombinant human insulin or analogues with residue substitutions that alter absorption rate

GLP-1 receptor agonist — acylated GLP-1 analog

Dual glucagon / GLP-1 receptor agonist based on oxyntomodulin

Non-peptide small-molecule GLP-1 receptor agonist — orally bioavailable

Triple GLP-1 / GIP / glucagon receptor agonist

GLP-1 receptor agonist — 31-amino-acid acylated analog of human GLP-1

Melanocortin-4 receptor (MC4R) agonist — cyclic octapeptide

Dual glucagon / GLP-1 receptor agonist

Dual GIP / GLP-1 receptor agonist — 39-amino-acid acylated peptide

GHRH analog; the DAC version bears a maleimide linker that binds serum albumin

Growth hormone-releasing peptide — synthetic hexapeptide ghrelin mimetic

First-generation growth hormone-releasing hexapeptide

Synthetic hexapeptide GH secretagogue

Modified insulin-like growth factor 1 analog with reduced binding-protein affinity

Selective ghrelin receptor (GHS-R1a) agonist — pentapeptide

Orally active ghrelin receptor agonist — peptidomimetic

Non-peptide, orally active ghrelin receptor agonist — listed here because it is universally marketed alongside peptides

Truncated GHRH analog — first 29 amino acids of human GHRH

191-amino-acid recombinant human growth hormone — a protein, not a short peptide

Stabilised growth hormone-releasing hormone (GHRH) analog

11-amino-acid peptide derived from the helix B region of erythropoietin

Synthetic pentadecapeptide derived from a sequence in human gastric juice protein BPC

Synthetic tripeptide Ala-Glu-Asp, one of the Khavinson short peptide bioregulators, designed from the composition of an animal cartilage polypeptide extract

Arginate salt form of the BPC-157 pentadecapeptide

Synthetic 25-residue fusion peptide: an octa-arginine cell-penetrating domain, a tetraglycine linker and a 13-residue Dishevelled-binding motif copied from CXXC5

Thymosin beta-4 is a 43-amino-acid actin-sequestering protein; TB-500 is a synthetic active fragment

C-terminal tripeptide fragment of alpha-melanocyte-stimulating hormone

Polypeptide complex extracted from calf thymus — a mixture, not a single molecule

Naturally occurring 28-amino-acid thymic peptide

Endogenous 28-amino-acid neuropeptide

Porcine brain-derived peptide preparation — a mixture, not a single molecule

Eight-amino-acid fragment of activity-dependent neuroprotective protein (ADNP)

Angiotensin IV analog — small oligopeptide HGF/c-Met potentiator

Dipeptide-derived nootropic — a proline-containing dipeptide ethyl ester

Heptapeptide fragment of spadin — residues 22-28 of the sortilin propeptide; selective blocker of the TREK-1 two-pore-domain potassium channel

Synthetic heptapeptide analog of the immunomodulatory peptide tuftsin

Synthetic heptapeptide analog of ACTH (4-10) with no corticotropic activity

Cardiolipin-targeting mitochondrial tetrapeptide

Synthetic tetrapeptide modelled on the pineal extract epithalamin

Retro-inverso D-amino acid peptide targeting the FOXO4-p53 interaction

TGF-beta superfamily protein, closely homologous to myostatin (GDF-8)

Mitochondrial-derived peptide — 24 amino acids

Synthetic tetrapeptide Lys-Glu-Asp-Ala, one of the Khavinson short peptide bioregulators, designed from the amino acid composition of a calf-liver polypeptide extract

Mitochondrial-derived peptide — 16 amino acids encoded in mitochondrial DNA

Dinucleotide coenzyme, not a peptide — nicotinamide mononucleotide joined to adenosine monophosphate by a pyrophosphate bridge; a redox carrier and enzyme substrate in every living cell

Selective MC1R agonist — alpha-MSH analog

Non-selective melanocortin receptor agonist (MC1R/MC3R/MC4R/MC5R)

Melanocortin receptor agonist (MC3R/MC4R) — cyclic heptapeptide

Synthetic gonadotropin-releasing hormone — decapeptide identical to the endogenous hormone

Glycoprotein hormone with an LH-like beta subunit — technically a glycoprotein rather than a simple peptide

Decapeptide fragment of kisspeptin, the master regulator of GnRH release

Synthetic cyclic octapeptide somatostatin analogue, disulfide-bridged and D-amino acid substituted; formulated as a supersaturated aqueous gel that self-assembles into a depot without a polymer carrier

GnRH receptor superagonist — nonapeptide analog of gonadotropin-releasing hormone

Synthetic cyclic octapeptide analogue of somatostatin, cyclised by a disulfide bridge and built with D-amino acids that resist enzymatic breakdown

Endogenous nonapeptide hormone

Octapeptide tight-junction regulator (zonulin antagonist)

Guanylate cyclase-C agonist — 14-amino-acid peptide with three disulfide bridges

Guanylate cyclase-C agonist — 16-amino-acid uroguanylin analog

GLP-2 receptor agonist — 33-amino-acid analog resistant to DPP-4

Cyclic cationic polypeptide antibiotic with a fatty acyl tail

Cyclic lipopeptide antibiotic — 13 amino acids with a decanoyl fatty acid tail

Human cathelicidin antimicrobial peptide — 37 residues

Glycopeptide antibiotic — a heavily modified, glycosylated seven-residue peptide

Endogenous heptapeptide of the renin-angiotensin system — angiotensin II minus its C-terminal phenylalanine; agonist at the Mas (MAS1) receptor

Synthetic vasopressin analog — nonapeptide selective for the V2 receptor

Recombinant human B-type natriuretic peptide — 32 amino acids

Recombinant human nerve growth factor — a 118-amino-acid protein

Cyclic undecapeptide of fungal origin, containing several non-standard amino acids

Synthetic N-acetylated tetrapeptide C-terminal amide, Ac-Lys-Gly-His-Lys-NH2 — the GHK matrikine motif extended by an N-terminal lysine

Copper(II) complex of the synthetic tripeptide Ala-His-Lys — GHK with alanine in place of the N-terminal glycine

Synthetic hexapeptide modelled on the N-terminal end of SNAP-25

Vitamin-peptide conjugate: the tripeptide GHK (Gly-His-Lys) with biotin amide-bonded to the glycine N-terminus

Naturally occurring copper-binding tripeptide

Unmodified linear pentapeptide Gly-Pro-Ile-Gly-Ser, free at both termini; originally isolated from a bacterial culture broth and now made synthetically

Lipidated pentapeptide — a collagen fragment conjugated to palmitic acid

Lipidated tripeptide — the GHK sequence conjugated to palmitic acid

Synthetic octapeptide — an elongated analog of Argireline

Synthetic 34-residue analogue of human parathyroid hormone-related protein PTHrP(1-34), with substitutions that bias it toward the RG conformation of the PTH1 receptor

Peptidomimetic targeting prohibitin on adipose vasculature, fused to a pro-apoptotic domain

Nonapeptide isolated from rabbit cerebral venous blood during induced sleep

Recombinant follistatin isoform — an activin and myostatin-binding glycoprotein

Endogenous tripeptide antioxidant (glutamate-cysteine-glycine)

Recombinant human parathyroid hormone fragment — first 34 amino acids